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1.
J. bras. patol. med. lab ; 43(6): 413-423, dez. 2007. ilus, tab
Article in Portuguese | LILACS | ID: lil-477627

ABSTRACT

O Staphylococcus aureus é uma bactéria do grupo dos cocos gram-positivos que faz parte da microbiota humana, mas que pode provocar doenças que vão desde uma infecção simples, como espinhas e furúnculos, até as mais graves, como pneumonia, meningite, endocardite, síndrome do choque tóxico e septicemia, entre outras. Essa bactéria foi uma das primeiras a serem controladas com a descoberta dos antibióticos, mas, devido a sua enorme capacidade de adaptação e resistência, tornou-se uma das espécies de maior importância no quadro das infecções hospitalares e comunitárias. Neste artigo faremos uma revisão sobre esse agente infeccioso e as bases dos mecanismos das patologias por ele provocadas, de forma a ressaltar a necessidade de mantê-lo como alvo para o desenho de novos antibióticos.


Staphylococcus aureus is a bacterium from Gram-positive coccus group, which is part of the human microbiota. It may cause diseases that may vary from simple infections (i.e., pimples and furuncles) to severe infections, such as pneumonia, meningitis, endocarditis, toxic shock syndrome and septicemia, among others. This bacterium was one of the first bacteria affected by antibacterial agents, however, its ability of adaptation and resistance turns it into an important hospital and communitarian pathogenic species of great concern. In this article we will discuss some important points related to the S. aureus and the pathologies related to it to reinforce it as a target for the design of new antibiotics.

2.
Motriz rev. educ. fís. (Impr.) ; 13(3): 203-213, 2007. tab
Article in Portuguese | LILACS | ID: lil-482273

ABSTRACT

Nas últimas décadas a Educação Física assumiu diferentes objetivos, estando atualmente voltada principalmente para a educação construtivista e desenvolvimento psicomotor, utilizando o movimento. Simultaneamente, a população em geral e as crianças em particular, estão sofrendo cada vez mais de sobrepeso, obesidade e doenças associadas. As principais causas são o sedentarismo e dieta inadequada. Atividade física e dieta são utilizadas como terapia, mas acreditamos que tenham que ser consideradas principalmente para prevenção, com início já na infância por meio de informação e incentivo para o consumo de dieta saudável e prática de atividades físicas, fornecidos pelos pais e educadores físicos na escola.


Along last decades, Physical Education had different objectives, but now is directed mainly to a constructivist education and psychomotor development, using the movement. In parallel, population in general and children, in particular, is becoming more fat and suffering of obesity and associated diseases. The mainly causes are low physical activity and inadequate diet. Physical activity and diet have been used only as therapy, but we think that they must be considered mainly as prevention, starting at childhood with information and incentive to take a health diet and practice of physical activities, provided by the parents and physical educators at school.


Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Obesity/prevention & control , Physical Education and Training , Breast Feeding , Brazil/epidemiology , Diet , Chronic Disease/prevention & control , Exercise , Feeding Behavior , Obesity/epidemiology , Obesity/etiology , Parents , Teaching
3.
Rev. bras. farmacogn ; 12(supl.1): 55-56, 2002. ilus
Article in English | LILACS | ID: lil-528750

ABSTRACT

The aqueous extract (AE) and isolated fraction (ppt-3) of Cuphea carthagenensis (Jacq.) J. F. Macbr (sete-sangrias) were tested using models of nociception and inflammation in mice. Oral administration (p.o.) of the AE (10 to 100 mg/kg) and fraction ppt-3 (0.1 to 10 mg/kg) reduced the acetic acid-induced writhing in mice by 40 to 50 percent and by 46 to 70 percent of control, respectively. At the same doses AE and ppt-3 did not affect the tail flick response. Fraction ppt-3 also reduced the carrageenininduced paw edema, but at a dose 1000 times higher than that inducing antinociception. The results indicated the presence in the plant of antinociceptive constituents devoid of antiinflammatory activity, with actions apparently mediated by non-opioid mechanisms.

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